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UPDATE: Big Picture in Vaping-Linked Lung Poisonings Over the last three months, the news has been filled with stories of peoplemostly youngfalling seriously ill from a mystery lung ailment supposedly caused by vaping

A number of independent observations show that cigarette smoke increases expression of the ACE2 gene: Mice exposed to cigarette smoke daily for 5 months had up to 80% more ACE2 expression in the lung compared with control mice Human lung epithelial cells from the bronchi of smokers had 30-55% more ACE2 expression than cells from non-smokers Lung samples from patients who smoked more than 80 pack-years had 100% more ACE2 expression than those who smoked less than 20 pack-years Quitting smoking was associated with a 40% decrease in ACE2 expression In murine and human lung, ACE2 is expressed at high levels in secretory and goblet cells and alveolar type 2 cells

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Since then, the agency has been asked to produce more evidence on the effectiveness of picture labels on each pack and some of that research is being done at the Annenberg Public Policy Center